Buffalo Bills at San Francisco 49ers
| Team | 1 | 2 | 3 | 4 | Score | Status |
| Buffalo Bills | 0 | 17 | 10 | 7 | 34 | |
| San Francisco 49ers | 7 | 0 | 10 | 7 | 24 | Final |
| Scoring Summary | |
| 1st Q | |
| 0:44 | San Francisco 49ers touchdown. Brandon Aiyuk 2 Yd pass from Nick Mullens (Robbie Gould Kick) |
| 2nd Q | |
| 13:02 | Buffalo Bills touchdown. Cole Beasley 5 Yd pass from Josh Allen (Tyler Bass Kick) |
| 2:41 | Buffalo Bills touchdown. Dawson Knox 4 Yd pass from Josh Allen (Tyler Bass Kick) |
| 0:00 | Buffalo Bills field goal. Tyler Bass 37 Yd Field Goal |
| 3rd Q | |
| 11:14 | San Francisco 49ers field goal. Robbie Gould 45 Yd Field Goal |
| 5:48 | Buffalo Bills touchdown. Isaiah McKenzie 23 Yd pass from Josh Allen (Tyler Bass Kick) |
| 3:09 | Buffalo Bills field goal. Tyler Bass 28 Yd Field Goal |
| 0:26 | San Francisco 49ers touchdown. Kyle Juszczyk 6 Yd pass from Nick Mullens (Robbie Gould Kick) |
| 4th Q | |
| 9:50 | Buffalo Bills touchdown. Gabriel Davis 28 Yd pass from Josh Allen (Tyler Bass Kick) |
| 0:43 | San Francisco 49ers touchdown. Jordan Reed 5 Yd pass from Nick Mullens (Robbie Gould Kick) |
| Team stats | ||
| First down | Buffalo Bills | San Francisco 49ers |
| Total first downs | 31 | 24 |
| First downs from rushing | 6 | 5 |
| First downs from passing | 22 | 18 |
| First downs from penalties | 3 | 1 |
| Third down | Buffalo Bills | San Francisco 49ers |
| Third downs attempted | 9 | 11 |
| Third downs converted | 4 | 6 |
| Third down percentage | 44 % | 55 % |
| Fourth down | Buffalo Bills | San Francisco 49ers |
| Fourth downs attempted | 3 | 1 |
| Fourth downs converted | 2 | 0 |
| Fourth down percentage | 67 % | 0 % |
| Offense | Buffalo Bills | San Francisco 49ers |
| Total yards | 449 | 402 |
| Total rushing yards | 81 | 86 |
| Total passing yards | 368 | 316 |
| Total offensive plays | 68 | 60 |
| Average yards per play | 10 | 9 |
| Time of possession | 34:58 | 25:02 |
| Rushing | Buffalo Bills | San Francisco 49ers |
| Total rushing plays | 27 | 21 |
| Total rushing yards | 81 | 86 |
| Average yards per rush | 3.0 | 4.1 |
| Rushing touchdowns | 0 | 0 |
| Passing | Buffalo Bills | San Francisco 49ers |
| Passes attempted | 40 | 39 |
| Passes completed | 32 | 26 |
| Average yards per completion | 9.0 | 8.1 |
| Passing touchdowns | 4 | 3 |
| Penalties | Buffalo Bills | San Francisco 49ers |
| Penalties committed | 4 | 7 |
| Penalty yards | 50 | 43 |
| Turnovers | Buffalo Bills | San Francisco 49ers |
| Passes intercepted | 0 | 2 |
| Interception returns | 0 | 2 |
| Interception return yards | ||
| Fumbles | ||
| Fumbles lost | 1 | 0 |
| Rushing | |||||||||
| Buffalo Bills | Rushes | Yards | Yards/rush | TD | Long | ||||
| Devin Singletary | 18 | 61 | 3.4 | 0 | 15 | ||||
| Josh Allen | 6 | 11 | 1.8 | 0 | 6 | ||||
| Zack Moss | 3 | 9 | 3.0 | 0 | 7 | ||||
| San Francisco 49ers | Rushes | Yards | Yards/rush | TD | Long | ||||
| Jeff Wilson Jr. | 7 | 47 | 6.7 | 0 | 18 | ||||
| Raheem Mostert | 9 | 42 | 4.7 | 0 | 16 | ||||
| Kyle Juszczyk | 2 | 5 | 2.5 | 0 | 5 | ||||
| Deebo Samuel | 1 | 3 | 3.0 | 0 | 3 | ||||
| Tevin Coleman | 2 | -11 | -5.5 | 0 | -2 | ||||
| Passing | |||||||||
| Buffalo Bills | Att | Comp | Comp % | Yards | Yards/pass | TD | Int | Sacks/Yards | QB Rating |
| Josh Allen | 40 | 32 | 80 % | 375 | 9.4 | 4 | 0 | 1-7 | 75.2 |
| San Francisco 49ers | Att | Comp | Comp % | Yards | Yards/pass | TD | Int | Sacks/Yards | QB Rating |
| Nick Mullens | 39 | 26 | 67 % | 316 | 8.1 | 3 | 2 | 0-0 | 70.4 |
| Receiving | |||||||||
| Buffalo Bills | Catches | Yards | Yards/catch | TD | Long | ||||
| Cole Beasley | 9 | 130 | 14.4 | 1 | 35 | ||||
| Stefon Diggs | 10 | 92 | 9.2 | 0 | 18 | ||||
| Gabriel Davis | 3 | 68 | 22.7 | 1 | 28 | ||||
| Isaiah McKenzie | 2 | 31 | 15.5 | 1 | 23 | ||||
| Dawson Knox | 4 | 27 | 6.8 | 1 | 12 | ||||
| Devin Singletary | 3 | 22 | 7.3 | 0 | 9 | ||||
| Zack Moss | 1 | 5 | 5.0 | 0 | 5 | ||||
| Lee Smith | 0 | 0 | 0.0 | 0 | 0 | ||||
| San Francisco 49ers | Catches | Yards | Yards/catch | TD | Long | ||||
| Brandon Aiyuk | 5 | 95 | 19.0 | 1 | 49 | ||||
| Deebo Samuel | 6 | 73 | 12.2 | 0 | 23 | ||||
| Kendrick Bourne | 4 | 35 | 8.8 | 0 | 13 | ||||
| Charlie Woerner | 2 | 33 | 16.5 | 0 | 18 | ||||
| Jordan Reed | 3 | 32 | 10.7 | 1 | 17 | ||||
| Ross Dwelley | 2 | 29 | 14.5 | 0 | 17 | ||||
| Jeff Wilson Jr. | 2 | 12 | 6.0 | 0 | 7 | ||||
| Kyle Juszczyk | 1 | 6 | 6.0 | 1 | 6 | ||||
| Raheem Mostert | 1 | 1 | 1.0 | 0 | 1 | ||||
| Fumbles | |||||||||
| Buffalo Bills | Lost | Recovered | Total | ||||||
| Josh Allen | 1 | 0 | 2 | ||||||
| San Francisco 49ers | Lost | Recovered | Total | ||||||
| Fred Warner | 0 | 1 | 0 | ||||||
| Interceptions | |||||||||
| Buffalo Bills | Total | Yards | Int TDs | ||||||
| Micah Hyde | 1 | 33 | 0 | ||||||
| Tre'Davious White | 1 | 0 | 0 | ||||||
| San Francisco 49ers | Total | Yards | Int TDs | ||||||
| None | |||||||||
| Defense | |||||||||
| Buffalo Bills | Tackles | Unassist. tkl | TFL | Pass def. | QB hits | Int TD | K blocked | K ret. TD | |
| Micah Hyde | 12 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | |
| Levi Wallace | 10 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | |
| Tremaine Edmunds | 7 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Jordan Poyer | 7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Taron Johnson | 6 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Tre'Davious White | 4 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | |
| A.J. Klein | 4 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | |
| Vernon Butler | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | |
| Matt Milano | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | |
| Darryl Johnson | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | |
| Quinton Jefferson | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Reid Ferguson | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| AJ Epenesa | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Harrison Phillips | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Ed Oliver | 1 | 0 | 0.5 | 0 | 1 | 0 | 0 | 0 | |
| Justin Zimmer | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
| San Francisco 49ers | Tackles | Unassist. tkl | TFL | Pass def. | QB hits | Int TD | K blocked | K ret. TD | |
| Jason Verrett | 11 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | |
| Dontae Johnson | 8 | 7 | 0 | 1 | 1 | 0 | 0 | 0 | |
| Jimmie Ward | 7 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Dre Greenlaw | 6 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Fred Warner | 6 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | |
| Tarvarius Moore | 6 | 3 | 0.5 | 0 | 0 | 0 | 0 | 0 | |
| Arik Armstead | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Richard Sherman | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kerry Hyder Jr. | 3 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Kevin Givens | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | |
| Dion Jordan | 3 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | |
| Javon Kinlaw | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Jordan Willis | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Mike McGlinchey | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Jeff Wilson Jr. | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Marcell Harris | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Joe Walker | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kick returns | |||||||||
| Buffalo Bills | Total | Yards | Avg | Long | TD | Kick ret. TD | |||
| Andre Roberts | 1 | 25 | 25.0 | 25 | 0 | 0 | |||
| San Francisco 49ers | Total | Yards | Avg | Long | TD | Kick ret. TD | |||
| Richie James | 1 | 13 | 13.0 | 13 | 0 | 0 | |||
| Punt returns | |||||||||
| Buffalo Bills | Total | Yards | Avg | Long | TD | ||||
| Andre Roberts | 1 | 22 | 22.0 | 22 | 0 | ||||
| San Francisco 49ers | Total | Yards | Avg | Long | TD | ||||
| Brandon Aiyuk | 1 | 16 | 16.0 | 16 | 0 | ||||
| Kicking | |||||||||
| Buffalo Bills | FG | Long | Extra Pt | Points | |||||
| Tyler Bass | 2/2 | 37 | 4/4 | 10 | |||||
| San Francisco 49ers | FG | Long | Extra Pt | Points | |||||
| Robbie Gould | 1/1 | 45 | 3/3 | 6 | |||||
| Punting | |||||||||
| Buffalo Bills | Total | Yards | Avg | Touchbacks | Inside 20 | Long | |||
| Corey Bojorquez | 1 | 68 | 68.0 | 0 | 0 | 68 | |||
| San Francisco 49ers | Total | Yards | Avg | Touchbacks | Inside 20 | Long | |||
| Mitch Wishnowsky | 2 | 90 | 45.0 | 0 | 1 | 54 | |||
Last updated on Tuesday, December 8, 2020 11:18 PM.