San Francisco 49ers at Los Angeles Rams
| Team | 1 | 2 | 3 | 4 | Final |
| San Francisco 49ers | 3 | 7 | 7 | 15 | 32 |
| Los Angeles Rams | 14 | 17 | 14 | 3 | 48 |
| Scoring Summary | |
| 1st Qtr | |
| 11:57 | Los Angeles Passing Touchdown - Brandin Cooks 3 yd pass from Jared Goff (Greg Zuerlein kick) |
| 10:42 | Los Angeles Rushing Touchdown - C.J. Anderson 1 yd run (Greg Zuerlein kick) |
| 2:11 | San Francisco Field Goal - Robbie Gould 30 yd FG |
| 2nd Qtr | |
| 12:37 | Los Angeles Interception Return - Cory Littleton 19 yd interception return (Greg Zuerlein kick) |
| 6:00 | Los Angeles Passing Touchdown - Brandin Cooks 18 yd pass from Jared Goff (Greg Zuerlein kick) |
| 2:07 | San Francisco Passing Touchdown - Richie James Jr. 9 yd pass from Nick Mullens (Robbie Gould kick) |
| 0:00 | Los Angeles Field Goal - Greg Zuerlein 28 yd FG |
| 3rd Qtr | |
| 12:19 | Los Angeles Passing Touchdown - Josh Reynolds 29 yd pass from Jared Goff (Greg Zuerlein kick) |
| 8:23 | San Francisco Rushing Touchdown - Alfred Morris 1 yd run (Robbie Gould kick) |
| 2:58 | Los Angeles Passing Touchdown - Josh Reynolds 2 yd pass from Jared Goff (Greg Zuerlein kick) |
| 4th Qtr | |
| 11:44 | Los Angeles Field Goal - Greg Zuerlein 51 yd FG |
| 6:54 | San Francisco Passing Touchdown - Kendrick Bourne 2 yd pass from Nick Mullens (Robbie Gould kick) |
| 2:20 | San Francisco Passing Touchdown - George Kittle 43 yd pass from Nick Mullens (Trent Taylor 2pt Pass from Nick Mullens) |
| Team Stats | ||
| First Downs | San Francisco | Los Angeles |
| First Downs Made | 22 | 28 |
| First From Rushing | 5 | 12 |
| First From Passing | 13 | 13 |
| First From Penalties | 4 | 3 |
| Third Downs | San Francisco | Los Angeles |
| Third Downs Attempted | 11 | 16 |
| Third Downs Converted | 3 | 10 |
| Third Down Percentage | 27 | 63 |
| Fourth Downs | San Francisco | Los Angeles |
| Fourth Downs Attempted | 1 | 1 |
| Fourth Downs Converted | 1 | 0 |
| Fourth Down Percentage | 100 | 0 |
| Yardage | San Francisco | Los Angeles |
| Total Net Yards | 391 | 377 |
| Total Rushing Yards | 127 | 155 |
| Total Passing Yards | 264 | 222 |
| Total Offensive Plays | 58 | 71 |
| Average Yards Per Play | 6.7 | 5.3 |
| Rushing | San Francisco | Los Angeles |
| Rushing Plays | 22 | 42 |
| Average Yards Per Rush | 5.8 | 3.7 |
| Rushing Touchdowns | 1 | 1 |
| Passing | San Francisco | Los Angeles |
| Passes Attempted | 33 | 29 |
| Passes Completed | 23 | 17 |
| Passes Intercepted | 3 | 0 |
| Average Yards Per Completion | 7.3 | 7.7 |
| Passing Touchdowns | 3 | 4 |
| Defense | San Francisco | Los Angeles |
| Tackles | 47 | 35 |
| Sacks | 0 | 3 |
| Sack Yards | 0 | 18 |
| Forced Fumbles | 0 | 1 |
| Punts | San Francisco | Los Angeles |
| Punts Kicked | 2 | 3 |
| Punts Returned | 0 | 2 |
| Average Punt Distance | 49.5 | 43.3 |
| Total Yards From Punt Returns | 0 | 11 |
| Kickoffs | San Francisco | Los Angeles |
| Kickoffs Kicked | 6 | 8 |
| Kickoffs Returned | 1 | 0 |
| Total Yards From Kickoff Returns | 25 | 0 |
| Penalties | San Francisco | Los Angeles |
| Penalties Committed | 5 | 6 |
| Penalty Yards | 41 | 57 |
| Turnovers | San Francisco | Los Angeles |
| Interception Returns | 0 | 3 |
| Interception Return Yards | 0 | 41 |
| Fumbles | 1 | 2 |
| Fumbles Lost | 1 | 0 |
| Scoring | San Francisco | Los Angeles |
| Extra Points Attempted | 3 | 6 |
| Extra Points Made | 3 | 6 |
| Field Goals Attempted | 1 | 2 |
| Field Goals Made | 1 | 2 |
| Two Point Conversions Attempted | 1 | 0 |
| Two Point Conversions Made | 1 | 0 |
| Time of Possession | San Francisco | Los Angeles |
| Total Time of Possession | 28:10 | 31:50 |
| Game Officials | |
| Referee | Jerome Boger |
| Umpire | Bill Schuster |
| Head Linesman | Mike Carr |
| Line Judge | Rusty Baynes |
| Field Judge | Dale Shaw |
| Side Judge | Scott Novak |
| Back Judge | Tony Steratore |
| Replay Official | John McGrath |
Attendance: 72,161
Game Length: 3:15
Information last updated on 1/11/2019 4:59:12 PM.