Jacksonville Jaguars at Buffalo Bills
| Team | 1 | 2 | 3 | 4 | Final |
| Jacksonville Jaguars | 0 | 14 | 0 | 7 | 21 |
| Buffalo Bills | 14 | 0 | 0 | 10 | 24 |
| Scoring Summary | |
| 1st Qtr | |
| 5:02 | Buffalo Rushing Touchdown - Isaiah McKenzie 6 yd run (Stephen Hauschka kick) |
| 2:39 | Buffalo Passing Touchdown - Robert Foster 75 yd pass from Josh Allen (Stephen Hauschka kick) |
| 2nd Qtr | |
| 10:58 | Jacksonville Rushing Touchdown - Leonard Fournette 5 yd run (Josh Lambo kick) |
| 5:30 | Jacksonville Rushing Touchdown - Leonard Fournette 1 yd run (Josh Lambo kick) |
| 4th Qtr | |
| 14:52 | Buffalo Rushing Touchdown - Josh Allen 14 yd run (Stephen Hauschka kick) |
| 3:06 | Buffalo Field Goal - Stephen Hauschka 22 yd FG |
| 1:20 | Jacksonville Passing Touchdown - Dede Westbrook 13 yd pass from Blake Bortles (Josh Lambo kick) |
| Team Stats | ||
| First Downs | Jacksonville | Buffalo |
| First Downs Made | 25 | 18 |
| First From Rushing | 13 | 9 |
| First From Passing | 6 | 5 |
| First From Penalties | 6 | 4 |
| Third Downs | Jacksonville | Buffalo |
| Third Downs Attempted | 13 | 10 |
| Third Downs Converted | 5 | 2 |
| Third Down Percentage | 38 | 20 |
| Fourth Downs | Jacksonville | Buffalo |
| Fourth Downs Attempted | 0 | 0 |
| Fourth Downs Converted | 0 | 0 |
| Fourth Down Percentage | - | - |
| Yardage | Jacksonville | Buffalo |
| Total Net Yards | 333 | 327 |
| Total Rushing Yards | 226 | 167 |
| Total Passing Yards | 107 | 160 |
| Total Offensive Plays | 65 | 54 |
| Average Yards Per Play | 5.1 | 6.1 |
| Rushing | Jacksonville | Buffalo |
| Rushing Plays | 39 | 35 |
| Average Yards Per Rush | 5.8 | 4.8 |
| Rushing Touchdowns | 2 | 2 |
| Passing | Jacksonville | Buffalo |
| Passes Attempted | 23 | 19 |
| Passes Completed | 12 | 8 |
| Passes Intercepted | 2 | 0 |
| Average Yards Per Completion | 4.1 | 8.4 |
| Passing Touchdowns | 1 | 1 |
| Defense | Jacksonville | Buffalo |
| Tackles | 34 | 48 |
| Sacks | 0 | 3 |
| Sack Yards | 0 | 20 |
| Forced Fumbles | 2 | 0 |
| Punts | Jacksonville | Buffalo |
| Punts Kicked | 6 | 7 |
| Punts Returned | 2 | 3 |
| Average Punt Distance | 47.8 | 44.9 |
| Total Yards From Punt Returns | 33 | 13 |
| Kickoffs | Jacksonville | Buffalo |
| Kickoffs Kicked | 4 | 5 |
| Kickoffs Returned | 3 | 3 |
| Total Yards From Kickoff Returns | 62 | 66 |
| Penalties | Jacksonville | Buffalo |
| Penalties Committed | 10 | 13 |
| Penalty Yards | 90 | 80 |
| Turnovers | Jacksonville | Buffalo |
| Interception Returns | 0 | 2 |
| Interception Return Yards | 0 | 12 |
| Fumbles | 0 | 2 |
| Fumbles Lost | 0 | 0 |
| Scoring | Jacksonville | Buffalo |
| Extra Points Attempted | 3 | 3 |
| Extra Points Made | 3 | 3 |
| Field Goals Attempted | 1 | 1 |
| Field Goals Made | 0 | 1 |
| Two Point Conversions Attempted | 0 | 0 |
| Two Point Conversions Made | 0 | 0 |
| Time of Possession | Jacksonville | Buffalo |
| Total Time of Possession | 32:42 | 27:18 |
| Game Officials | |
| Referee | Walt Coleman |
| Umpire | Jeff Rice |
| Head Linesman | Jerry Bergman |
| Line Judge | Mark Stewart |
| Field Judge | Greg Gautreaux |
| Side Judge | Jabir Walker |
| Back Judge | Greg Yette |
| Replay Official | Darryll Lewis |
Attendance: 57,799
Game Length: 3:22
Information last updated on 11/28/2018 5:23:19 PM.