| 7:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 901 CINCINNATI | T Wood-L | 4 | 135 | ||
| 902 PITTSBURGH | R Ohlendorf-R | 0 | FINAL | 7½ov | |
| Box Score | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 903 N.Y. METS | J Santana-L | 1 | 6½ov | ||
| 904 ATLANTA | T Hudson-R | 4 | FINAL | 140 | |
| Box Score | |||||
| 8:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 905 Milwaukee | Y Gallardo-R | 18 | 115 | ||
| 906 CHICAGO CUBS | R Wells-R | 1 | FINAL | 8ov | |
| Box Score | |||||
| 8:15 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 907 HOUSTON | B Myers-R | 9 | 7½un | ||
| 908 ST. LOUIS | J Westbrook-R | 4 | FINAL | 160 | |
| Box Score | |||||
| 9:40 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 909 Washington | L Hernandez-R | 3 | 9½ | ||
| 910 ARIZONA | R Lopez-R | 1 | FINAL | 125 | |
| Box Score | |||||
| 10:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 911 SAN DIEGO | C Richard-L | 10 | 6½ov | ||
| 912 L.A. Dodgers | H Kuroda-R | 5 | FINAL | 135 | |
| Box Score | |||||
| 7:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 913 Toronto | B Morrow-R | 8 | 9½un | ||
| 914 N.Y. Yankees | A Burnett-R | 6 | FINAL | 185 | |
| Box Score | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 915 Minnesota | C Pavano-R | 2 | 8 | ||
| 916 TAMPA BAY | J Hellickson-R | 4 | FINAL | 120 | |
| Box Score | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 917 CLEVELAND | F Carmona-R | 6 | 9un | ||
| 918 Boston | J Lackey-R | 5 | FINAL | 200 | |
| Box Score | |||||
| 10:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 919 Kansas City | B Bannister-R | 0 | 7½ov | ||
| 920 Oakland | T Cahill-R | 6 | FINAL | 230 | |
| Box Score | |||||