| 4:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 901 L.A. Dodgers | C Billingsley-R | 1 | 7½ | ||
| 902 SAN FRANCISCO | B Zito-L | 2 | FINAL | 110 | |
| Box Score Line Moves | |||||
| 7:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 903 PHILADELPHIA | J Blanton-R | 5 | 130 | ||
| 904 Washington | R Detwiler-L | 7 | FINAL | 9un | |
| Box Score Line Moves | |||||
| 7:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 905 Milwaukee | D Bush-R | 0 | 8 | ||
| 906 HOUSTON | W Rodriguez-L | 6 | FINAL | 110 | |
| Box Score Line Moves | |||||
| 4:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 907 ATLANTA | J Jurrjens-R | 2 | 8 | ||
| 908 CINCINNATI | B Arroyo-R | 5 | FINAL | 110 | Time Change |
| Box Score Line Moves | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 909 ARIZONA | B Enright-R | 4 | 8½un | ||
| 910 N.Y. METS | H Takahashi-L | 5 | FINAL | 145 | |
| Box Score Line Moves | |||||
| 7:15 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 911 PITTSBURGH | D McCutchen-R | 1 | 9½un | ||
| 912 ST. LOUIS | J Suppan-R | 11 | FINAL | 190 | |
| Box Score Line Moves | |||||
| 8:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 913 CHICAGO CUBS | T Gorzelanny-L | 5 | 9ov | ||
| 914 COLORADO | J Hammel-R | 6 | FINAL | 160 | |
| Box Score Line Moves | |||||
| 8:35 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 915 FLORIDA | R Nolasco-R | 6 | 6½ov | ||
| 916 SAN DIEGO | K Correia-R | 3 | FINAL | 115 | |
| Box Score Line Moves | |||||
| 1:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 917 CLEVELAND | J Tomlin-R | 2 | 8½ | Pitching Change | |
| 918 Toronto | B Cecil-L | 1 | FINAL | 215 | 12:25E |
| Box Score Line Moves | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 919 SEATTLE | F Hernandez-R | 0 | 7½ | ||
| 920 Minnesota | K Slowey-R | 4 | FINAL | 110 | Time Change |
| Box Score Line Moves | |||||
| 4:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 921 Detroit | M Scherzer-R | 4 | 8½ov | ||
| 922 Boston | D Matsuzaka-R | 5 | FINAL | 180 | |
| Box Score Line Moves | |||||
| 7:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 923 Oakland | D Braden-L | 6 | 7½ov | ||
| 924 Chicago W. Sox | J Danks-L | 2 | FINAL | 160 | |
| Box Score Line Moves | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 925 Baltimore | B Bergesen-R | 3 | 8½ov | ||
| 926 Kansas City | Z Greinke-R | 4 | FINAL | 220 | |
| Box Score Line Moves | |||||
| 7:10 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 927 N.Y. Yankees | J Vazquez-R | 5 | 8½ov | ||
| 928 TAMPA BAY | M Garza-R | 4 | FINAL | 115 | |
| Box Score Line Moves | |||||
| 9:05 PM EST | Pitcher | Final Score | Closing Line | Notes | |
| 929 Texas | R Harden-R | 2 | 9un | ||
| 930 L.A. ANGELS | D Haren-R | 1 | FINAL | 150 | |
| Box Score Line Moves | |||||
| 3:30 PM EST | Final Score | Closing Line | Notes | ||
| 8105 New England | 1 | +250 | +215 | ||
| 8106 Philadelphia | 1 | FINAL | -105 | 2½un30 | |
| 4:00 PM EST | Final Score | Closing Line | Notes | ||
| 8109 FC Dallas | 1 | +215 | +210 | ||
| 8110 Colorado | 1 | FINAL | +110 | 2½un50 | |
| 8:30 PM EST | Final Score | Closing Line | Notes | ||
| 8113 New York | 2 | +210 | +215 | ||
| 8114 Houston | 2 | FINAL | +105 | 2½un35 | |
| 8:30 PM EST | Final Score | Closing Line | Notes | ||
| 8117 Toronto | 0 | +235 | +215 | ||
| 8118 Kansas City | 1 | FINAL | +100 | 2½un45 | |
| 9:00 PM EST | Final Score | Closing Line | Notes | ||
| 8121 D.C. United | 0 | +500 | +250 | ||
| 8122 Real Salt Lake | 3 | FINAL | -200 | 2½ov20 | |
| 10:00 PM EST | Final Score | Closing Line | Notes | ||
| 8125 Seattle | 1 | +215 | +215 | ||
| 8126 San Jose | 0 | FINAL | -105 | 2½ov20 | |
| 10:30 PM EST | Final Score | Closing Line | Notes | ||
| 8129 Columbus | 1 | +160 | +215 | ||
| 8130 Chivas USA | 3 | FINAL | +140 | 2½un40 | |
| 7:00 PM EST | Final Score | Closing Line | Notes | ||
| 357 Milwaukee | 54 | 118½ | |||
| 358 Cleveland | 47 | FINAL | 2 | ||
| Box Score Line Moves | |||||
| 7:30 PM EST | Final Score | Closing Line | Notes | ||
| 359 Orlando | 75 | 103 | |||
| 360 Tampa Bay | 60 | FINAL | 8 | ||
| Box Score Line Moves | |||||
| 8:00 PM EST | Final Score | Closing Line | Notes | ||
| 361 Dallas | 62 | 6 | |||
| 362 Bossier Shreveport | 56 | FINAL | 105 | ||
| Box Score Line Moves | |||||
| 8:30 PM EST | Final Score | Closing Line | Notes | ||
| 363 Utah | 64 | 103½ | |||
| 364 Alabama | 68 | FINAL | 12 | ||
| Box Score Line Moves | |||||
| 6:35 PM EST | Final Score | Closing Line | Notes | ||
| 415 Hamilton | 24 | 55 | |||
| 416 Saskatchwan | 37 | FINAL | 7½ | ||
| Box Score Line Moves | |||||
| 9:35 PM EST | Final Score | Closing Line | Notes | ||
| 417 Winnipeg | 18 | 55 | |||
| 418 Calgary | 23 | FINAL | 6½ | ||
| Box Score Line Moves | |||||